The 2002 Doha Declaration reaffirmed that the TRIPS Agreement should not prevent members from taking the necessary measures to protect public health. Despite this recognition, less developed countries have argued that flexible TRIPS provisions, such as compulsory licensing, are almost impossible to enforce. Less developed countries, in particular, cited their young domestic manufacturing and technology industries as evidence of the imprecision of the policy. The TRIPS Agreement introduced intellectual property rights into the multilateral trading system for the first time and remains the most comprehensive multilateral agreement on intellectual property to date. In 2001, developing countries, concerned about the industrialized countries` insistence on an overly narrow interpretation of TRIPS, launched a round table that resulted in the Doha Declaration. The Doha Declaration is a WTO declaration that clarifies the scope of TRIPS and, for example, states that TRIPS can and should be interpreted with the aim of "promoting access to medicines for all". The general transitional periods apply to original WTO members, i.e. governments that were members on 1 January 1995. Since the WTO, a number of countries have acceded to it. These countries have generally agreed, in their accession agreements (accession protocols), to apply the TRIPS Agreement from the date on which they officially became members of the WTO, without a transitional period benefiting from a transitional period. The Agreement on trade aspects of intellectual property rights (TRIPS) is an international agreement between all member states of the World Trade Organization (WTO). It establishes minimum standards for the regulation of different forms of intellectual property (IP) by national governments, as applied to nationals of other WTO member countries.  TRIPS was negotiated at the end of the Uruguay Round of the General Agreement on Tariffs and Trade (GATT) between 1989 and 1990 and is managed by the WTO.
Pursuant to Article 4(d), a Member may exempt from the most-favoured-nation obligation all advantages, advantages, privileges or immunities of that Member under international agreements for the defence of intellectual property which entered into force before the entry into force of the WTO Agreement, provided that such agreements are notified to the Ad Hoc Council and do not constitute arbitrary or unjustifiable discrimination against nationals of other members. The TRIPS Council comprises all WTO members. It shall be responsible for monitoring the functioning of the Agreement and, in particular, the manner in which Members fulfil their obligations under the Agreement. Prior to the Uruguay Round 198694 negotiations, there was no specific agreement on intellectual property rights under the GATT multilateral trading system. The WTO is a forum for further negotiations to strengthen intellectual property obligations, as well as in other areas covered by WTO agreements. Article 69 of the Agreement obliges members to establish and notify within their administrations contact points in order to cooperate with each other in order to interrupt trade in goods contrary to the law. .